L’inattivazione biallelica di TP53 (TP53 double hit) è stata inclusa nella definizione di mieloma multiplo double hit, caratterizzato da prognosi...

Nonostante i grandi progressi nell’ambito del mieloma multiplo, le recidive sono frequenti e la malattia continua a essere caratterizzata da...

In our study, time to initiation of systemic therapy was an independent prognostic factor in MM

This study aimed to develop reliable nomogram-based predictive models that could guide prognostic stratification and individualized treatments in...

The patients were divided into two groups according to the optimal value of the HALP score (low-score group: HALP ≤28.8 [n: 134] and high-score group...

The expression of select genes associated with the production of various enzymes and proteins involved in glycolysis and oxidative phosphorylation...

Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for the detection and measurement of cancer

Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes nearly all cases of multiple myeloma...

Commensal microbes not only can influence host immunity locally through impacts of bioactive microbial metabolites and direct interactions with...

This multistage process requires tumor cells to enter the circulation, extravasate, and colonize distant bone marrow (BM) sites

Sarcopenia or low muscle mass is related to worse prognosis in cancer patients. We investigated whether muscle mass is related to bone damage on CT in...

This review discusses the role of immune dysfunction at the different stages of MM