Gli autori hanno identificato la filogenesi della popolazione tumorale subclonale e ne hanno ricavato l’architettura evolutiva in ciascun paziente

In summary, our study contributes to growing evidence suggesting that high BMI or obesity may be a risk factor for progression from MGUS to MM...

Our findings suggest that multiple myeloma patients with double/triple hit cytogenetics on FISH have aggressive presentations, high early mortality...

NGS approaches should be considered as a replacement technique for a more comprehensive evaluation of the multiple myeloma clone

PLR was a robust prognostic factor for newly diagnosed early-stage cHL

Gli studiosi si sono posti l’obiettivo di analizzare il ruolo e i meccanismi della proteina di riconoscimento della metilazione YTHDF1 (YTH N6...

Dal momento che, nell’ambito dell’immunosoppressione, il rischio di tumore associato a virus è aumentato, è stata effettuata un’analisi metagenomica...

Circ_0016347 functioned as an oncogene in osteosarcoma at least in part by the miR-661/IL6R axis and JAK2/STAT3 signalling pathway

We conclude that MM survivors who achieve disease control after AHCT have excellent recovery of FACT-BMT and subscale scores to population norms by 1...

CD138+ overexpression of miR-181a was strongly correlated with inferior disease outcome and contributed to superior prediction of MM patients early...

This high-risk group presents diverse previously known genetic markers, but also a new characteristic defined by accumulation of genomic loss which...

Sono necessari ulteriori studi su questi pazienti ad altissimo rischio per migliorare la gestione della malattia, studi che potrebbero fornire...