Up to 30 000 cells were acquired and IGH chromosomal abnormalities were detected in 5 of the 10 marrow samples. FISH signal patterns seen included...

This study aimed to develop reliable nomogram-based predictive models that could guide prognostic stratification and individualized treatments in...

Per quanto riguarda l’individuazione di traslocazioni ricorrenti e CNV gli autori hanno evidenziato alta concordanza tra i risultati di lrWGS e di...

Lo studio considera l’impiego di saggio di digital PCR (ddPCR, digital PCR) per validare una firma genetica precedentemente identificata tramite l...

The patients were divided into two groups according to the optimal value of the HALP score (low-score group: HALP ≤28.8 [n: 134] and high-score group...

Multiple myeloma (MM) is characterized by copy number abnormalities (CNAs), some of which influence patient outcomes and are sometimes observed only...

The expression of select genes associated with the production of various enzymes and proteins involved in glycolysis and oxidative phosphorylation...

Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for the detection and measurement of cancer

Therefore, systemic study on IgD MM is purposeful to disclose the recurrent and refractory features in both IgD and other types of MM, and beneficial...

Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes nearly all cases of multiple myeloma...

Commensal microbes not only can influence host immunity locally through impacts of bioactive microbial metabolites and direct interactions with...

Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast...