Ad oggi, hanno analizzato i campioni di 525 pazienti con mieloma multiplo di nuova diagnosi (campioni sia midollari che di sangue periferico) e hanno...

Up to 30 000 cells were acquired and IGH chromosomal abnormalities were detected in 5 of the 10 marrow samples. FISH signal patterns seen included...

Per quanto riguarda l’individuazione di traslocazioni ricorrenti e CNV gli autori hanno evidenziato alta concordanza tra i risultati di lrWGS e di...

Lo studio considera l’impiego di saggio di digital PCR (ddPCR, digital PCR) per validare una firma genetica precedentemente identificata tramite l...

Multiple myeloma (MM) is characterized by copy number abnormalities (CNAs), some of which influence patient outcomes and are sometimes observed only...

La medicina di precisione costituisce un approccio particolarmente rilevante in ambito oncologico, relativamente a tumore e microambiente tumorale...

Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for the detection and measurement of cancer

Therefore, systemic study on IgD MM is purposeful to disclose the recurrent and refractory features in both IgD and other types of MM, and beneficial...

Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast...

Despite the improvement of therapeutic regimens, several patients with multiple myeloma (MM) still experience early relapse (ER). This subset of...

This retrospective cohort study used 2013-2018 commercial and Medicare claims data to assess medication use in adults with MM

To evaluate impact of time to transplant on subsequent outcomes, we analyzed data on consecutive MM patients who received novel agents-based induction...