The expression of select genes associated with the production of various enzymes and proteins involved in glycolysis and oxidative phosphorylation...

Circulating tumor DNA (ctDNA) has offered a minimally invasive approach for the detection and measurement of cancer

Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes nearly all cases of multiple myeloma...

Commensal microbes not only can influence host immunity locally through impacts of bioactive microbial metabolites and direct interactions with...

This multistage process requires tumor cells to enter the circulation, extravasate, and colonize distant bone marrow (BM) sites

Sarcopenia or low muscle mass is related to worse prognosis in cancer patients. We investigated whether muscle mass is related to bone damage on CT in...

This review discusses the role of immune dysfunction at the different stages of MM

In this study, we explored the potential prognostic value of IRGs in MM by combining GEP and clinical data from the GEO database

To evaluate impact of time to transplant on subsequent outcomes, we analyzed data on consecutive MM patients who received novel agents-based induction...

Questo studio ha valutato in modo retrospettivo gli outcome di 25.423 pazienti (16.744 con MGUS, 6.194 con mieloma multiplo, 2.955 con amiloidosi AL)

Gli autori hanno utilizzato una combinazione di PET-CT e di GEP (gene expression profiling), su cellule di mieloma multiplo CD138+ di midollo osseo...

Nello studio gli autori hanno valutato in modo retrospettivo 1347 pazienti con mieloma multiplo recidivato