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Mieloma multiplo
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Oncoematologia
Articolo scientifico

Reduced CXCR4 expression in associated with extramedullary and predicts poor survival in newly diagnosed multiple…

10.02.2023

Multiple myeloma (MM), a bone marrow-resident hematological malignancy of plasma cells, has remained largely incurable despite the recent advancement...

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

Circulating Tumor and Immune Cells for Minimally Invasive Risk Stratification of Smoldering Multiple Myeloma

10.02.2023

Early intervention in smoldering multiple myeloma (SMM) requires optimal risk stratification to avoid under- and overtreatment

Prognosi
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Oncoematologia
Articolo scientifico

Time to first treatment is an independent prognostic factor for Multiple Myeloma (MM)

1 min
●
31.01.2023

In our study, time to initiation of systemic therapy was an independent prognostic factor in MM

Prognosi
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Oncoematologia
Articolo scientifico

IGH cytogenetic abnormalities can be detected in multiple myeloma by imaging flow cytometry

1 min
●
31.01.2023

Up to 30 000 cells were acquired and IGH chromosomal abnormalities were detected in 5 of the 10 marrow samples. FISH signal patterns seen included...

Diagnosi
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Oncoematologia
Articolo scientifico

Application of clinical nomograms to predicting overall survival and event-free survival in multiple myeloma patients:…

1 min
●
31.01.2023

This study aimed to develop reliable nomogram-based predictive models that could guide prognostic stratification and individualized treatments in...

Prognosi
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Oncoematologia
Articolo scientifico

In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present From Diagnosis in Tiny,…

1 min
●
31.01.2023

Multiple myeloma (MM) is characterized by copy number abnormalities (CNAs), some of which influence patient outcomes and are sometimes observed only...

Diagnosi
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Oncoematologia
Articolo scientifico

The effect of haemoglobin, albumin, lymphocyte and platelet score on the prognosis in patients with multiple myeloma

1 min
●
31.01.2023

The patients were divided into two groups according to the optimal value of the HALP score (low-score group: HALP ≤28.8 [n: 134] and high-score group...

Prognosi
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Oncoematologia
Articolo scientifico

Overexpression of the energy metabolism transcriptome within clonal plasma cells is associated with the pathogenesis and…

11.11.2022

The expression of select genes associated with the production of various enzymes and proteins involved in glycolysis and oxidative phosphorylation...

Patogenesi, Prognosi
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Oncoematologia
Articolo scientifico

A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow…

11.11.2022

Therefore, systemic study on IgD MM is purposeful to disclose the recurrent and refractory features in both IgD and other types of MM, and beneficial...

Diagnosi
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Oncoematologia
Articolo scientifico

Body mass index and risk of progression from monoclonal gammopathy of undetermined significance to multiple myeloma:…

11.11.2022

Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor condition that precedes nearly all cases of multiple myeloma...

Prognosi
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Oncoematologia
Articolo scientifico

Host-microbe interactions and outcomes in multiple myeloma and hematopoietic stem cell transplantation

11.11.2022

Commensal microbes not only can influence host immunity locally through impacts of bioactive microbial metabolites and direct interactions with...

Prognosi
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Oncoematologia
Articolo scientifico

Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple…

11.11.2022

Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast...

Diagnosi

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Patologie

Mieloma multiplo
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