We aimed to investigate the clinical utility of the International Myeloma Working Group (IMWG) frailty score in the setting of relapsed or refractory...

This study will help optimize the delivery of safe, low-cost, and scalable telehealth exercise interventions to improve health outcomes in patients...

The NONO protein belongs to the multifunctional family of proteins that can bind DNA, RNA and proteins. It is located in the nucleus of most mammalian...

Per molti anni sono state effettuate analisi intensive per comprendere in modo approfondito la patogenesi del mieloma multiplo

RNA sequencing data and corresponding clinical information were acquired from Multiple Myeloma Research Foundation (MMRF)-COMMPASS and served as a...

Multiple myeloma is an incurable hematologic malignancy, its early diagnosis is important. However, the biomarker for early diagnosis is limited...

Multiple myeloma (MM), a bone marrow-resident hematological malignancy of plasma cells, has remained largely incurable despite the recent advancement...

Early intervention in smoldering multiple myeloma (SMM) requires optimal risk stratification to avoid under- and overtreatment

L’inattivazione biallelica di TP53 (TP53 double hit) è stata inclusa nella definizione di mieloma multiplo double hit, caratterizzato da prognosi...

L’elettroforesi delle proteine sieriche contenute nelle urine e l’immunofissazione sono le tecniche d’elezione per il monitoraggio delle proteine...

Nonostante i grandi progressi nell’ambito del mieloma multiplo, le recidive sono frequenti e la malattia continua a essere caratterizzata da...

Gli autori si sono posti l’obiettivo di identificare nuove varianti pleiotropiche coinvolte nel rischio di mieloma multiplo, utilizzando 28.684...