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Articolo scientifico
Immagine standard per news
Oncoematologia
Articolo scientifico

In Multiple Myeloma, High-Risk Secondary Genetic Events Observed at Relapse Are Present From Diagnosis in Tiny,…

1 min
●
31.01.2023

Multiple myeloma (MM) is characterized by copy number abnormalities (CNAs), some of which influence patient outcomes and are sometimes observed only...

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

A novel protein encoded by circHNRNPU promotes multiple myeloma progression by regulating the bone marrow…

11.11.2022

Therefore, systemic study on IgD MM is purposeful to disclose the recurrent and refractory features in both IgD and other types of MM, and beneficial...

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple…

11.11.2022

Extensive genetic and transcriptional characterization of myeloma has identified subtypes with prognostic and therapeutic implications. In contrast...

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

Development and Validation of a Simplified Score to Predict Early Relapse in Newly Diagnosed Multiple Myeloma in a…

11.11.2022

Despite the improvement of therapeutic regimens, several patients with multiple myeloma (MM) still experience early relapse (ER). This subset of...

Diagnosi
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Oncoematologia
Articolo scientifico

Development and Validation of a Simplified Score to Predict Early Relapse in Newly Diagnosed Multiple Myeloma in a…

29.07.2022

On the basis of simple, widely available baseline features, the S-ERMM and DS-ERMM properly identified patients with different risks of ER and...

Diagnosi
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Oncoematologia
Articolo scientifico

Prediction of High-Risk Cytogenetic Status in Multiple Myeloma Based on Magnetic Resonance Imaging: Utility of Radiomics…

29.07.2022

The LR classifier performed better than the other classifiers based on different data (AUC: 0.65-0.82; P < 0.05)

Diagnosi, Innovazione
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Oncoematologia
Articolo scientifico

Clinical characteristics and survival outcomes of newly diagnosed multiple myeloma patients presenting with…

20.07.2022

We retrospectively reviewed and compared the clinical features and outcomes in 226 MM patients with or without EMD at their diagnosis

Diagnosi
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Oncoematologia
Articolo scientifico

Pre-existing hypertension is associated with poor progression-free survival in newly diagnosed multiple myeloma patients

20.07.2022

Our study demonstrates that pre-existing hypertension was significantly associated with a lower PFS in newly diagnosed MM patients

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

Impact of autologous transplantation on survival in patients with newly diagnosed multiple myeloma who have high-risk…

20.07.2022

The magnitude of OS benefit with upfront HDT is cytogenetics-dependent. Patients with high-risk cytogenetics should preferably receive upfront rather...

Diagnosi
Immagine standard per news
Oncoematologia
Articolo scientifico

Relapse after complete response in newly diagnosed multiple myeloma: implications of duration of response and patterns…

01.06.2022

This is likely attributable to underlying disease biology and prevention of end-organ damage by early treatment initiation, as benefit was independent...

Diagnosi

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Patologie

Mieloma multiplo
Oncoematologia

Temi

Disease awareness
Prognosi
Diagnosi
Gestione del paziente
Patogenesi
Trattamento
Innovazione
Quality of life
Efficacia

Tipologia

Articolo scientifico